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A pH responsive nanocontainer based on hydrazone bearing

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Intracellular pH-responsive and rituximab-conjugated mesoporous silica nanoparticles for targeted drug delivery to lymphoma B cells | Journal of .

Rituximab-conjugated mesoporous silica nanoparticles SEM: Scaning electron microscope TEM: ... Tan L, Yang MY, Wu HX, Tang ZW, Xiao JY, Liu CJ, et al. Glucose- and pH-responsive nanogated ensemble based on polymeric network capped mesoporous ...

Engineering a Hollow Nanocontainer Platform with Multifunctional Molecular Machines for Tumor-Targeted Therapy in Vitro and in Vivo | ACS Na

A pH-responsive nanocontainer based on hydrazone-bearing hollow silica nanoparticles for targeted tumor therapy. Journal of Materials Chemistry B 2016, 4 (26) ...

Kaiyong Cai | Ph D | Chongqing University, Chongqing | CQU | Department of Biological Engineering | ResearchGa

A pH-responsive nanocontainer based on hydrazone-bearing hollow silica nanoparticles for targeted tumor therapy Article Jan 2016 Liangliang Dai ...

Frontiers | Hydrazone-Containing Triblock Copolymeric Micelles for pH-Controlled Drug Delivery | Pharmacolo

In this work, it was started with rational designing of PEG-based marcro-initiators with hydrazone bond imbedded, ... The pH-responsive release of the hydrazone containing micelles might underwent a cleavage-disassociation-release process. FIGURE 6 Figure 6 ...

A pH-responsive stellate mesoporous silica based nanophotosensitizer for in vivo cancer diagnosis and targeted photodynamic therapy. | PubFac

Development of a photosensitizer that can achieve tumor specificity, improve therapeutic efficacy, and reduce side effects remains a challenge for photodynamic therapy (PDT). In this work, a pH-sensitive activatable nanophotosensitizer (SMSN-ZnPc1) has been ...

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JNM Journal of Nanomaterials 1687-4129 1687-4110 Hindawi Publishing Corporation 408675 10.1155/2011/408675 408675 Review Article Emerging Technologies of Polymeric Nanoparticles in Cancer Drug Delivery Brewer Erik Coleman Jason Lowman Anthony Sun Lu ...

Development of the Novel PEG-PE-Based Polymer for the Reversible Attachment of Specific Ligands... - Europe PMC Article - Europe P

... easily via a pH-responsive reversible hydrazone bond. Proteins avidin, Con-A and monoclonal antibodies 2C5 and 2G4 were successfully immobilized on the liposome surface via the pH responsive hydrazone bond. Various ...

Frontiers | Recent Progress and Advances in Stimuli-Responsive Polymers for Cancer Therapy | Bioengineering and Biotechnolo

A polymer nanocarrier system with a stimuli-responsive property (e.g., pH, temperature, or redox potential), for example, would be amenable to address the intracellular delivery barriers by taking advantage of pH, temperature, ...

Helics Gro

Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo. ACS Applied Materials & Interfaces, 2014, 6: 7395-7407.

pH-Responsive Mesoporous Silica and Carbon Nanoparticles ... - Core - MAFIADOC.C

Chen T, Fu J. pH-responsive nanovalves based on hollow. Mesoporous silica nanoparticles synthesized from 2013 Lin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution â Non Commercial (unported ...

Co-delivery of doxorubicin and pH-sensitive curcumin prodrug by transferrin-targeted nanoparticles for breast cancer treatme

Stimuli-responsive and prodrug-based nanoassemblies have many advantages as a potent platform for co-delivery of anticancer drugs, ... Co-delivery of doxorubicin and pH-sensitive curcumin prodrug by transferrin-targeted nanoparticles for breast cancer //doi.org ...

CN102475891A - PH-responsive polyethylene glycol-anticarcinogen conjugate, and synthetic method and application thereof - Google Paten

The invention discloses a pH-responsive polyethylene glycol-anticarcinogen conjugate, and a synthetic method and application thereof. After anticarcinogen molecules and polyethylene glycol are covalently linked through pH-sensitive phenylimide linkage, the ...

Targeted pharmacokinetics of polymeric micelles modified with glycyrrhetinic acid and hydrazone bond in H22 tumor-bearing mice - Yan Zheng, Shudan .

Targeted pharmacokinetics of polymeric micelles modified with glycyrrhetinic acid and hydrazone bond in H22 tumor-bearing mice Yan Zheng, Shudan Shi, Yaru Liu, Yandan Zhao, and Yuqi Sun ...

Progress in Polymer Scien

hydrazone,imine,cis-acotinyl,andoxime,whichhydrolyze rapidly in the endosomal compartment (pH ∼5). ... of block copolymer, or at the sidechain,leadingtothefacileandrobustdevelopment ofnewstrategiestowardthepreparation pH-responsive polymeric drug with ...

Bioengineering | Free Full-Text | pH-Responsive Mesoporous Silica and Carbon Nanoparticles for Drug Delivery | HT

There are also systems based on pH-responsive hydroxyapatite nanoparticles. As these nanoparticles degrade when pH drops, they only allow the release in tumoral tissues and have the advantage of being biocompatible, even after dissolving ...

Self-Assembly Assisted Fabrication of Dextran-Based Nanohydrogels with Reduction-Cleavable Junctions for Applications as Efficient Drug Delivery .

In addition, the flexibility of the SAA fabrication methodology was shown to be effective in the fabrication of dextran-based NGs when another carboxyl group-bearing monomer, methacrylic acid (MAA), ...

A pH-responsive prodrug delivery system of 10-HCPT for controlled release and tumor targeting (pdf) | Paperi

More from International Journal of Nanomedicine Folic acid-functionalized drug delivery platform of resveratrol based on... Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed ...

Photochemically Triggered Cytosolic Drug Delivery Using pH-Responsive Hyaluronic Acid Nanoparticles for Light-Induced Cancer Therapy .

A photochemically triggered cytosolic drug delivery system based on combining tumor-targeting pH-responsive hyaluronic acid (HA) nanoparticles (PHANs) with anticancer therapeutics (doxorubicin; DOX) was successfully developed for light-induced cancer therapy.

Multistage pH-responsive mesoporous silica nanohybrids with charge reversal and intracellular release for efficient anticancer drug delive

This study introduced multistage pH-responsive nanohybrids (MSN-hyd-MOP) based on mesoporous silica nanoparticles (MSNs) modified with polymers with charge-reversal property via a